Associate Director / Director, Translational Genetics
Empirico Inc.
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Associate Director / Director, Translational Genetics

Empirico Inc.

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Details
Posted:
February 12, 2021
Location:
San Diego, California
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PayScale
Type:
Full Time - Experienced
Years of Experience:
5 - 10
Organization Type:
Other / Not Specified
Required Education:
Doctorate

Location:  San Diego, CA

Position Description: Empirico, an early-stage biotechnology company, is looking for a director-level computational geneticist experienced in analyzing and interpreting large scale human genetics data for the purpose of therapeutic target discovery. This is an excellent opportunity for a highly-motivated, creative scientist to be a vital member of a team of experts dedicated to identifying new disease targets and translating those insights into therapeutic programs.

Responsibilities:

Your responsibilities will include using human genetics data to identify new therapeutic targets in order to advance Empirico’s drug discovery and development pipeline. You will be expected to:

  • Work with a multidisciplinary team consisting of human geneticists, bioinformaticians and software engineers to lead the design, execution, and interpretation of in silico human genetic studies
  • Discover novel genetic associations with human diseases using Empirico’s world-leading target discovery platform
  • Provide genetic intelligence on therapeutic targets of interest for external collaborators
  • Create and deliver expert-level presentations that clearly communicate genetic discoveries and stories to colleagues, collaborators and investors
  • Translate findings from genetic studies into therapeutic hypotheses and contribute to decisions around therapeutic modality and targeting strategies
  • Collaborate with biologists and chemists on the design of in vitro and in vivo experiments to validate therapeutic hypotheses that are motivated by human genetics findings
  • Provide novel ideas and critical thinking for the continued development and improvement of Empirico’s target discovery platform
  • Survey the latest developments in the broader genetics community and incorporate relevant approaches and findings into internal studies

Requirements:

  • This position requires an MD or PhD with at least 4-6 years of postgraduate experience in human genetics research with a translational focus. Pay and title commensurate with experience
  • Core background MUST be in computational genetics; this position is NOT for scientists with a primarily wet-lab background
  • A firm understanding of the principles of statistical genetics and genetic epidemiology
  • Demonstrated ability to design, lead and interpret human genetics studies and to discern therapeutic hypotheses
  • Familiarity with the design of functional studies to understand the mechanistic basis for genetic associations
  • Applicants must have authorization to work in the U.S.

About Empirico Inc.
Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.
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