The research program of the Wells lab at the Vanderbilt University Medical Center is directed toward understanding the phenotypic and genetic architecture of cardiovascular diseases. Ongoing projects focus on a range of cardiovascular phenotypes including heart failure, cardiac arrhythmias, obesity and cardiometabolic disease, valvular heart disease, and peripheral arterial disease. The overarching goal of our lab is to understand how phenotypic and genetic variation in individuals and populations contributes to variable disease susceptibility and therapeutic response, and then translate this knowledge to patient-centered, precision care. We conduct studies across a range of populations using a variety of techniques. A major interest is leveraging the power of the electronic health record (EHR) for genomic and pharmacogenomics studies. We collaborate extensively with other investigators, including national and international consortia. Our studies utilize a range of techniques including candidate and genome-wide association, whole exome sequencing, polygenic risk scores, gene-gene and gene-environment interactions, and proteomics/metabolomics studies. The successful candidate will have opportunity to lead and participate in projects with large-scale consortium datasets, and the EHR-linked Vanderbilt Biobank (BioVU). He/she will work in a team environment. He/she will oversee, supervise, plan, design and implement research projects, including applying existing genetics, statistics and bioinformatics tool and/or develop new methods such as machine learning to analyze data from the research projects. He/she will summarize and present results for written reports and oral presentations and contribute in manuscript and grant writing. He/she will train and advise analytical staff, students, post-doctoral fellows and faculty. He/she will also assist the principal investigator to manage the lab and computing resources.
Independently oversee research projects and perform near to totally independent research.
Supervise, plan, design and implement research projects
Establish highly complex protocol(s); define data collection, evaluation and analysis procedures
Exercise discretion and independent judgment to develop methods and procedures for operation of complex scientific equipment
Supervise set-up and operation of various scientific experiments involving complex apparatus and equipment
Contribute to research so as to merit serving as author or co-author on research publications, etc.
Assist principal investigator in writing research grants and contract proposals
Assists principal investigator in manuscript preparation for scientific journals.
Present research findings as needed
Responsible for planning and coordination of literature and library searches and data collection programs
Develop reports of results, graphs, charts, tables, etc. of research findings
Supervise writing, reviewing and editing of various materials for publication
Provide supervisory responsibility to staff
Mentor and teach graduate students and post-doctoral fellows in developing their projects and on specific techniques and protocols.
Train and supervise technical staff, medical and graduate students
Provide technical guidance to students, post-doctoral fellows and faculty as required
May provide budget responsibility
Make recommendations to principal investigator regarding staff, supply and equipment needs for research projects
Maintain open communication between department and others
Open contact as needed with principal investigator, collaborating professionals, Purchasing, Human Resource Services, Space and Facilities Planning, asset management personnel, Environmental Health and Safety, Institutional Review Board staff, administrative staff relating to budget capabilities
Contact as required with sponsoring agencies and/or cooperating facilities (e.g. V.A.), collaborating professionals and vendors
Internal Number: 1905183
About Vanderbilt University Medical Center
Vanderbilt University, located in Nashville, Tennessee, is a private research university offering a full range of undergraduate, graduate and professional degrees.
