A 3-yr postdoctoral position is available immediately in the laboratory of Dr. Caren Chang to investigate the signaling pathway of a novel plant hormone. Plants hormones such as ethylene control many aspects of plant biology. The small molecule 1-aminocyclopropane-1-carboxylic acid (ACC) is the well-known precursor in ethylene biosynthesis. Compelling new data from our lab (unpublished) suggests that ACC itself is a signaling molecule that impacts plant growth and development independent of ethylene. Moreover, this signal appears to have evolutionarily predated the ability of higher land plants to efficiently convert ACC to ethylene. The postdoc will dissect the ACC signaling pathway and investigate ACC as a signaling molecule using evolutionarily relevant model species, including Arabidopsis thaliana. Approaches include molecular genetics (e.g., mutant screens, knocking out specific genes) and the tools of cell biology to analyze aspects of fertilization, root growth, and development. Experience with Marchantia polymorpha and/or Physcomitrella patens is desirable. Skills in microscopy, Ca2+ imaging, or whole genome sequencing would be a plus. For more information about this project, please contact Dr. Chang at email@example.com. To apply, please send a CV, a brief statement of research experience and interests, and the names and email addresses of three references to firstname.lastname@example.org.
The Chang Lab is in the Department of Cell Biology and Molecular Genetics, and is located in the Bioscience Research Building at University of Maryland, College Park, in the Washington DC-Metro area just minutes from the nation's capital.